Pharmaceutical-Grade Vial&Bottle Cleaning Systems: Rinsing, Sterilization & Drying Solutions
High-speed rotating brush systems for thorough internal cleaning of bottles/tubs. Removes product residues, oils, and particulates. Features:
Pharma-grade: 316L SS, cleanroom-compatible
Multi-stage: Pre-rinse → hot-CIP → purified water final rinse
Throughput: Up to 24,000 containers/hour
Conveyor-based systems for external cleaning and pre-sterilization:
Spray Types: Reverse osmosis (RO) water, disinfectant mist, compressed air
Applications: Label adhesive removal, dust elimination
Integration: Inline with filling monoblocks
Non-contact cleaning using ionized air knives:
Zero Liquid: Ideal for moisture-sensitive packaging (powders, electronics)
Static Control: Removes dust while neutralizing ESD
| System Type | Key Features | Compliance |
|---|---|---|
| Rinse & Blow-Off | RO water spray + ionized air drying | ISO 9001 |
| Full Drying Modules | Heated HEPA-filtered air tunnels (residual moisture <0.1%) | FDA 21 CFR 211 |
| Multi-Cycle Washers | 3-stage process: Tap water → detergent → WFI/PW rinse | EU GMP Annex 1 |
| Sterilization Ready | Gamma radiation/SIP tunnels (SAL 10⁻⁶) | USP <1229> |
Semi-Automatic Benchtop Rinsers
Compact units for R&D/low-volume production. Manual loading → automatic internal/external rinsing. Ideal for pilot batches or clinic pharmacies.
Automatic Inline Washers
Conveyor-based systems for medium throughput (500-5,000 U/h). Integrated air-knife drying. Direct coupling with filling monoblocks.
Rotary High-Speed Complexes
Turret-based washers for 5,000-24,000 vials/hour. Multi-stage CIP cycles, laminar air drying. Full GMP validation support.
Cleaning Stages:
Nozzle Technology:
Rotating internal spray balls (360° coverage)
External jet arrays for label adhesive removal
Self-cleaning SIP/CIP capability
Material Traceability: 316L SS contact surfaces, FDA elastomers
| Feature | Pharma Impact |
|---|---|
| WFI/PW Compatibility | Validated water quality (EP/USP standards) |
| No Dead Legs | Tri-clamp connections, sloped surfaces (prevent biofilm) |
| Data Integrity | Electronic batch records + audit trails (21 CFR Part 11) |
| Change Parts | Vial nest tooling for 2ml-1000ml containers (changeover <20 mins) |
| Parameter | Rotary Washers | Tunnel Rinsers | Air Rinse |
|---|---|---|---|
| Capacity | 500–24,000 U/h | 1,000–30,000 U/h | 5,000–50,000 U/h |
| Cleaning Media | Water/steam/CIP fluids | Water/air/sanitizers | Ionized air only |
| Drying | Hot-air blowers | Air knives | Not required |
| Power | 15–50 kW | 5–20 kW | 2–8 kW |
| Sector | Solution | Critical Requirements |
|---|---|---|
| Pharma | WFI rinsing + depyrogenation tunnels | Endotoxin reduction <0.25 EU/ml |
| Veterinary | High-pressure pesticide removal | Solvent-resistant seals |
| Cosmetics | Essence/oil dissolution cycles | Non-abrasive PEEK brushes |
| Food | Allergen control protocols | EHEDG-certified design |
| Sector | Critical Features | Compliance |
|---|---|---|
| Pharma | WFI (Water for Injection) rinse, SIP cycles | GMP, FDA 21 CFR 211 |
| Food/Bev | Food-grade lubricants, allergen control | HACCP, EHEDG |
| Chemicals | Solvent-resistant seals, explosion-proofing | ATEX, IECEx |
| Cosmetics | Essence/oil removal, non-abrasive brushes | ISO 22716 |
| Market | Key Feature | Certification |
|---|---|---|
| Middle East | High-temp cooling (50°C ambient) | GSO |
| SE Asia | Monsoon-proof electricals | GMP |
| Africa | Low-water operation mode | SONCAP |
| EU | REACH-compliant chemicals | CE, EN 1672-2 |
Upstream Compatibility:
Glass/PET bottle production lines
IBC tote refurbishment
Downstream Partners:
Filling monoblocks
Inspection machines
RFC triblocks
Upstream: Ampoule washers, glass forming lines
Downstream:
Rinsing-Filling-Capping (RFC) monoblocks
Lyophilizer loading stations
Aseptic filling isolators
Inline Sensors: TOC monitoring, particulate counters
| Market | Standards | Documentation |
|---|---|---|
| USA | FDA 21 CFR 211, USP <1229> | IQ/OQ/PQ validation protocols |
| EU | EU GMP Annex 1, EN 285 | EMA audit support |
| Southeast Asia | PIC/S, WHO GMP | Local agent assistance |
| Middle East | SFDA, GSO | Arabic translation included |
Water Efficiency: 75% reduction vs manual washing (closed-loop filtration)
Quick Changeover: Tool-free adjustments for different container sizes
Sanitary Design: Self-draining surfaces, rounded corners (no biofilm traps)
Smart Monitoring: IoT sensors for TOC (Total Organic Carbon) control
Replaces manual washing with:
85% labor reduction in container prep
40% lower utility costs (water/energy)
Zero cross-contamination: Validated cleaning cycles
Scalability: From 50 to 50,000 units/hour
Unlike generic washers, our systems offer:
35% faster cycle times: Multi-nozzle rotary technology
Zero cross-contamination: Dedicated CIP circuits per fluid path
Scalable validation: From R&D to commercial batches
Global support: Commissioning engineers in 12 countries
Solve your cleaning challenges:
Pharma: Validated SIP/WFI systems
Food: Allergen control protocols
Chemicals: Solvent recovery options
Request a cleaning validation package:
Sterile products: SIP + endotoxin reduction reports
Ophthalmic preparations: Particle-free drying data
ATMPs: Closed-system configuration options
🌐 Request Compliance Audit: Free gap analysis with throughput simulation.
✅ GMP Compliance Guarantee
✅ 24/7 Multilingual Support
✅ 24-month performance guarantee
✅ Local technicians in 18 countries
Free line configuration for your products, throughput validation testing!
Contact Specialists for Packaging Equipment:
Compliance Roadmap:
