GMP-Compliant Integrated Packaging for Solid Dosage Forms.
Precision-Engineered Solid Dosage Packaging
Integrated rotary systems combining counting, bottle filling, cotton insertion, and induction sealing in ISO Class 8 environments — designed for GMP compliance of hard/soft gelatin capsules and coated tablets.
Precision Engineered for Pharma Integrity
Integrated counting, filling, cotton insertion, and sealing in ISO Class 8 equivalent environments — designed for uncompromised product protection of solid dosage forms.
Pharmaceutical-Grade Performance
| Parameter | Standard Specs | Premium Options |
|---|---|---|
| Throughput | 80-150 BPM | 300 BPM (high-speed) |
| Counting Accuracy | 100% ±0 tablets | Vision-verified |
| Container Range | 20-100mm jars | Vials to 1L bottles |
| Dosage Forms | Tablets • Hard Capsules | Softgels • Lozenges |
| Environmental Control | ISO Class 8 equivalent | Isolated RABS option |
| Compliance | GMP • 21 CFR Part 11 | EU Annex 1 |
Pharmaceutical-Grade Performance
| Parameter | Standard Range | Premium Options |
|---|---|---|
| Throughput | 80-150 BPM | 300 BPM (servo-driven) |
| Counting Accuracy | 100% ±0 tablets | Vision verification |
| Dosage Forms | Hard/Soft Gel Caps • Coated Tabs | Lozenges • Gummies |
| Container Compatibility | Glass/Plastic Bottles (20-200mm) | Vials • Jars |
| Environmental Control | ISO Class 8 Equivalent | Isolated RABS Option |
Precision Counting Mechanisms
| System | Best For | Accuracy | Speed |
|---|---|---|---|
| Rotary Disc Counter | Standard tablets/capsules | 100% ±0 | 200 units/min |
| Vibratory Feeder | Irregular shapes/sizes | 99.98% | 150 units/min |
| Multi-Lane Counter | High-volume production | 100% ±0 | 500 units/min |
| Vision-Verified | Coated/printed dosage forms | 100% defect-free | Custom |
Critical Compliance Features
Material Construction: AISI 316L SS contact surfaces
Cleanability: CIP/SIP capability, radiused corners
Data Integrity: Electronic batch records with audit trails
Change Control: Documented SAT/FAT protocols
Environmental: HEPA-filtered air showers
Seamless 8-Stage Processing
Bottle Unscrambling: Orientation verification
Precise Counting: Vibration-free disc technology
Gentle Transfer: Low-friction PU channels
Cotton Insertion: Anti-static placement (optional)
Induction Sealing: 1-5kW foil sealing
Torque Capping: 1-20Nm servo application
Quality Control: Checkweighing ±0.5g
Downstream Integration: Labeling • Cartoning
Critical Area Protection
HEPA-Filtered Enclosures: ISO 14644-1 Class 8
Material Pass-Throughs: Rapid transfer ports
GMP-Grade Surfaces: 316L SS • Pharma plastics
Contamination Control: Negative pressure zones
Optimized Dosage Form Handling
| Dosage Form | Special Features |
|---|---|
| Enteric-Coated Tabs | Anti-abrasion channels |
| Softgel Capsules | Temperature-controlled transfer |
| Hygroscopic Forms | <20% RH nitrogen-purged environment |
| Omega-3 Softgels | Cold-chain compatible components |
Enhanced Compliance & Efficiency
Isolation Technology: RABS or isolator integration
Track & Trace: Serialization modules (DSCSA/FMD compliant)
Vision Inspection: 100% defect detection
Nitrogen Flushing: <50ppm O₂ residual control
Complete Production Line Solutions
Why Pharmaceutical Manufacturers Choose Locus
✅ Zero Product Damage: <0.1% friability rate
✅ Rapid Changeovers: <10 mins between formats
✅ Regulatory Ready: IQ/OQ/PQ validation packages, Full validation packages
✅ Scale Flexibility: Modular capacity expansion
Global Regulatory Alignment
| Standard | Implementation |
|---|---|
| GMP (WHO/EU/US) | Full documentation packages |
| 21 CFR Part 11 | Audit trails • E-signatures |
| EU Annex 1 | Isolated critical zones |
| PIC/S | Cross-border compliance |
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