Description
The Ultimate Integrated Solution for Precision Filling and Finished Packaging
The LR-1000 Integrated Flow Meter Filling and Cartoning Monoblock represents the pinnacle of packaging automation for regulated industries. It transforms a complex, multi-stage process involving precision dosing, handling, and secondary packaging into a single, validated, and controlled operation. For manufacturers of injectable drugs, biologics, clinical trial materials, and premium cosmetics, this machine drastically reduces contamination risk, operational complexity, and floor space requirements while providing an unbroken chain of custody and data integrity from the bulk container to the sealed carton.
End-to-End Automation: From Bulk Liquid to Boxed Product
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Precision Filling: Vials, syringes, or bottles are fed into the integrated container orienter, ensuring perfect positioning. Each container is filled by a liquid flow meter (Coriolis mass flow meter) achieving fill accuracies of ±0.1% or better, critical for costly active ingredients.
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Stoppering/Sealing: Immediately after filling, containers are automatically sealed with stoppers, crimps, or screw caps within the protected zone of the monoblock.
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Integrated Cartoning: The sealed containers are automatically transferred to the integrated cartoning module. This machine forms cartons, inserts the containers (often with leaflets), and seals the cartons, creating a finished, retail-ready or shipper-ready unit.
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Discharge & Data Logging: Finished cartons are discharged onto a conveyor. Throughout the process, every critical parameter—fill weight, cap torque, carton serialization—is recorded by the central control system for full batch traceability.
Core Technology: Mass Flow Meters for Critical Accuracy
The system’s heart is its liquid flow meter (Coriolis) dosing technology. Unlike volumetric methods, Coriolis meters measure the mass of product directly, making the fill accuracy immune to changes in product viscosity, temperature, or the presence of bubbles. This provides:
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Unmatched Precision: Consistent fills at ±0.1% to ±0.25%, minimizing product giveaway.
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Inline Quality Control: Simultaneous density measurement for an additional real-time quality check.
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Complete Data: Each fill’s exact mass is recorded, supporting ALCOA+ principles for data integrity.
Technical Specifications of the Automated Packaging Cell
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Machine Type: Fully Integrated, Automated Monoblock (Flow Meter Filling + Sealing + Cartoning).
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Filling Technology: Coriolis Mass Flow Meters on each filling head.
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Secondary Packaging: Integrated automatic cartoning machine (vertical or horizontal).
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Process Features: Integrated container orienter, automatic feeding systems.
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Container Compatibility: Vials, syringes, bottles, ampoules.
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Output Speed: High-speed, synchronized output designed for batch production.
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Construction: Full cGMP-compliant, cleanroom-suitable design. AISI 316L Stainless Steel product contact parts.
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Control & Data: Unified PLC/Industrial PC platform with validated HMI. Supports electronic batch records, recipe management, and 21 CFR Part 11 compliant data handling.
Target Applications: Regulated and High-Value Industries
This monoblock is the ideal solution for sectors where precision, sterility, and documentation are paramount:
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Pharmaceutical & Biotech: Sterile injectables (vials, syringes), vaccines, ophthalmics, lyophilized products.
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Advanced Therapies: Cell and gene therapy products, clinical trial materials.
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Diagnostics & Medical Devices: Reagents, test kits, sample collection tubes.
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Premium Cosmetics & Dermatology: Injectable aesthetics, sterile skincare ampoules.
Engineered for Data Integrity, Traceability & Global Support
The LR-1000 is built for regulatory success. Its integrated design minimizes manual interventions, supporting sterility assurance. The centralized data system ensures full traceability from liquid to carton. We support this critical infrastructure with comprehensive validation packages (IQ/OQ/PQ), 24/7 global support from specialized engineers, and a dedicated spare parts program to ensure maximum uptime for your most valuable production lines worldwide.
📜 Schedule virtual airflow visualization test.
💡 Mention your: Target market (EU/US/Global South), Active ingredient, Required throughput.
🔬 Schedule virtual factory acceptance test with our engineers.
🏷️ Request Compliance Audit: Free gap analysis with throughput simulation.
🔍Ready to Eliminate Production Bottlenecks?
💎Need Industrial Production Automation?
✅ GMP Compliance Guarantee
✅ 24/7 Multilingual Support
✅ 24-month performance guarantee
✅ Local technicians in 18 countries
📈Start small, get a free production layout designed for your growth trajectory. Scale smarter with engineering support!
📥Free line configuration for your products, throughput validation testing!
🎓Contact Specialists for Packaging Equipment:
📄 On-Demand Engineering: Product-specific configurations in 1-2 weeks.
🔧 Spare Parts Kits: Region-specific inventory for <24hr delivery.
🧼Compliance Roadmap:
- CE, EAC, ISO 9001 certifications.
- GMP-ready: 316L SS contact parts, CIP/SIP capabilities.
- ATEX options for chemical solvents.





























